Turning 40 can bring changes you may not have expected. Your energy may feel different, recovery can take longer, your skin may not look quite the same, and even your sleep or digestion can change.

These changes are not necessarily a sign that something is wrong. Ageing naturally affects many processes in the body, while lifestyle, nutrition, stress and hormonal changes can all influence how you feel.

The good news is that there are practical ways to support your body as it changes. Here are seven everyday signs worth paying attention to — and some nutrients and ingredients that may be relevant.

1. Your energy isn't what it used to be

Feeling tired from time to time is normal. But if you regularly feel like you have less energy than you used to, it may be worth looking at your sleep, diet, stress levels and activity.

Certain botanical ingredients have also been studied for their potential role in energy and mental performance. Panax ginseng has been investigated in relation to fatigue and cognitive function, while Ginkgo biloba has been studied for its potential effects on cognitive health.

You can find both ingredients in Refine, where they are combined as part of a broader daily wellness formula.

2. Recovery takes longer

Maybe a workout that once left you feeling fine now means you need an extra day or two to recover. Maintaining muscle and physical function becomes increasingly important with age.

Research on ageing and skeletal muscle shows that muscle mass and physical function can gradually change with age, making regular physical activity and adequate nutrition increasingly important.

Vitamin D3 is another nutrient worth knowing about. According to the NIH Office of Dietary Supplements, vitamin D contributes to the maintenance of normal muscle function and is important for bone health.

Vitamin D3 is included in Enhance, alongside vitamin K2 and several plant-based oils and compounds.

3. Your joints and movement feel different

Stiffness after sitting or discomfort during movement can become more noticeable over time. Staying physically active is one of the most useful things you can do for long-term mobility.

Nutrition may also form part of the bigger picture. Avocado oil, grape seed oil and black cumin seed oil contain naturally occurring compounds that have attracted scientific interest for their nutritional and antioxidant properties.

For example, research has explored black cumin seed oil and its bioactive compound thymoquinone, although much of the evidence remains preliminary and does not establish a specific effect from consuming the oil in a finished supplement.

These oils are part of Enhance, together with resveratrol, vitamin D3 and K2.

4. Your skin seems less firm or hydrated

Changes in skin texture, elasticity and appearance are common as we age. Collagen production and the structure of the skin gradually change over time, while environmental exposure, nutrition and lifestyle can also influence its appearance.

Collagen, vitamin C, zinc and selenium are among the nutrients commonly associated with maintaining normal skin structure and protection from oxidative stress.

Research has also investigated whether oral collagen supplementation can influence skin parameters such as hydration and elasticity. A systematic review and meta-analysis of randomized controlled trials found evidence of potential benefits, while also highlighting the need for further research.

Vitamin C has a particularly clear nutritional role: according to the NIH Office of Dietary Supplements, it is required for collagen biosynthesis and contributes to normal collagen formation.

These ingredients are brought together in UGlow Beauty Boost Drink, which also contains MSM, vitamins B3 and B7, and CoQ10.

5. Your sleep pattern changes

You may notice that falling asleep, staying asleep or waking up refreshed isn't as easy as it once was.

Sleep changes can have many causes, including stress, lifestyle and normal ageing. Research from the National Institute on Aging notes that sleep patterns can change as people get older, including changes in sleep duration and the tendency to wake more often during the night.

Certain nutrients may also be relevant. Vitamin D3, for example, has been investigated for its relationship with sleep quality. A 2022 systematic review and meta-analysis found that vitamin D supplementation was associated with improved sleep quality, although the researchers noted that further research is needed to clarify its effects on different sleep problems. Vitamin D3 is included in Enhance.

Rather than looking for one ingredient to solve the problem, it makes sense to start with the basics: a consistent sleep schedule, regular movement, a balanced diet and good sleep habits.

6. Your digestion feels different

Changes in appetite, bowel habits or digestive comfort can become more noticeable with age.

Fibre-rich foods, enough fluids, regular movement and a varied diet remain important foundations. Research and guidance from the National Institute on Aging emphasize the importance of a nutrient-rich diet as part of healthy ageing.

Supplements should complement these habits rather than replace them.

If digestive symptoms are persistent, severe or unexplained, they should not simply be attributed to getting older and should be discussed with a healthcare professional.

7. You feel like your body needs more nutritional support

Perhaps the biggest change after 40 is that your body may no longer feel quite as forgiving of poor sleep, stress, inactivity or an inconsistent diet.

This is where a well-rounded approach can make sense. Vitamin C, for example, contributes to normal collagen formation and normal immune function, while zinc and selenium contribute to the protection of cells from oxidative stress, according to the NIH Office of Dietary Supplements and NIH Office of Dietary Supplements.

For people looking to combine several of these nutritional and botanical ingredients into one routine, the Trio Pack Plus brings together Refine, Enhance and VitaC. VitaC provides liposomal vitamin C, while the other two formulas add the botanical extracts, oils, vitamin D3 and K2 discussed above.

The simple answer

Feeling different after 40 is not automatically a cause for concern. Your body naturally changes with age, and factors such as sleep, nutrition, exercise, stress and hormonal changes can all contribute.

The goal isn't to stop ageing. It's to give your body the nutritional and lifestyle support it needs as those changes happen.

Ingredients such as ginkgo biloba, Panax ginseng, avocado oil, grape seed oil, black cumin seed oil, resveratrol, vitamins D3 and K2, and liposomal vitamin C can be part of that broader nutritional approach. For skin-focused nutritional support, collagen, MSM, vitamin C, zinc, selenium, vitamins B3 and B7, and CoQ10 are combined in UGlow Beauty Boost Drink.

What matters most is understanding that supplements are only one part of the picture. A balanced diet, regular movement, adequate sleep and appropriate healthcare remain the foundation of healthy ageing.

Research used in this article

• Panax ginseng and fatigue/cognitive function — PubMed
• Ginkgo biloba — National Center for Complementary and Integrative Health
• Ageing and skeletal muscle — PubMed
• Vitamin D — NIH Office of Dietary Supplements
• Black cumin seed / thymoquinone — PubMed
• Oral collagen supplementation and skin — PubMed
• Vitamin C — NIH Office of Dietary Supplements
• Sleep and ageing — National Institute on Aging
• Healthy eating and nutrition — National Institute on Aging
• Zinc — NIH Office of Dietary Supplements
• Selenium — NIH Office of Dietary Supplements

This article is for educational purposes only and is not intended to diagnose, treat or prevent any medical condition. Individual ingredients may have different levels of evidence, and research on an ingredient does not necessarily establish the same effect for a finished product. If you have persistent, severe or unexplained symptoms, speak with a qualified healthcare professional.